Rabbit Anti Human Crystallin-alpha C Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (IHC,ELISA) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.05% sodium azide and 50% glycerol, pH7.4 This antibody has been purified using Affinity Purified.

More Details:

• Host: Rabbit
• Species: Human,Mouse,Rat
• Target: Crystallin-alpha C
• Clonality: Polyclonal
• Purity: Affinity Purified
• Immunogen: Recombinant protein of human HSPB8
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

This product can be used in analytical tools such as IHC,ELISA.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.